Assistant Project Scientist Retinoid Metabolism in Lipid Drople
University of California, Berkeley
Berkeley, California 94720
Job Description and Requirements
Assistant Project Scientist Ã¢ Retinoid Metabolism in Lipid Droplets - Department Of Nutritional Sciences & Toxicology
The lab of Dr. Joseph Napoli, University of California-Berkeley, has developed LC/MS/MS techniques to quantify retinoids for assessing physiological atRA retinal and retinol levels in small amounts of tissues and cultured cells. The lab has also developed experimental mouse models of disrupted retinoid homeostasis. Combined, these tools allow interrogation of retinoid mechanisms of action in determining stem cell, regulating adiposity, bone health, and energy balance.
Job duties and responsibilities include: biochemical studies of retinoid metabolism, quantification of tissue and cell levels of retinoids by HPLC and LC/MS/MS, transgenic and knock out mouse colony management, harvesting primary mouse SVF and use in culture, mouse behavioral and metabolic phenotyping, management of junior lab personnel, and presenting oral and written reports, writing manuscripts, presenting reports in research symposia.
BASIC QUALIFICATIONS (at time of application)
Candidates must have completed a Ph.D. or equivalent degree in chemistry, biochemistry, molecular biology or neuroscience, or related field by the time of application, and a minimum of 3 yearsÃ¢ experience in experimental biology and biochemical laboratory studies of cellular metabolism.
ADDITIONAL QUALIFICATIONS (by start date)
Experience in quantification of physiological tissue and cell levels of retinoids by HPLC and LC/MS/MS in intact cells and sub-cellular fractions. A minimum of 3 years experience with mouse husbandry (transgenic and knock out mouse colony management), harvesting primary mouse SVF and their use in culture, and experience in mouse behavioral and metabolic phenotyping. The successful candidate should have a minimum of 3 years laboratory experience in adipose biology and metabolic phenotyping. The candidate should have a track record of successful management of junior lab personnel, including graduate students and research assistants, and will be expected to lead student researchers working on diverse projects. The position relies on demonstrated excellent oral and written communication ability for preparing project reports, manuscripts, and research symposium presentations.
In addition to the qualifications described above, preferred qualifications include atRA biosynthesis assays in cell culture and isolated sub-cellular fractions. Experience with oral and written communication for preparing project reports, manuscripts, and research symposium presentations is highly desired. Also highly desired are experience in mitochondrial respiration assays using Seahorse technology, and lipid uptake cellular assays using fluorescent analogs of fatty acids, as well as experience in liver, muscle, adipose and brain tissue histology, and fluorescent organelle labeling of live cells in culture, and advanced fluorescent microscopy imaging techniques, including real time live cellular imaging and laser scanning confocal microscopy.
The anticipated start date is Summer 2017. The initial appointment is for one year, with renewal based on performance and funding. This is a full-time appointment.
SALARY AND BENEFITS
The salary range for this position is $54,800-$70,900. Salary will be commensurate with qualifications and experience. Generous benefits are included (http://ucnet.universityofcalifornia.edu/compensation-and- benefits/health-plans/index.html).
Interested individuals should include a 1-2 page cover letter describing research experience, your most recently updated C.V., and the names and contact information of three references. Letters of reference may be requested for finalists. It is optional to include a statement addressing past and/or potential contributions to diversity through research, teaching, and/or service.
This position will remain open until filled.
Questions regarding this recruitment can be directed to Dr. Joseph Napoli at Jna@berkeley.edu .
All letters will be treated as confidential per University of California policy and California state law. Please refer potential referees, including when letters are provided via a third party (i.e. dossier service or career center) to the UC Berkeley Statement of Confidentiality (http://apo.berkeley.edu/evalltr.html) prior to submitting their letters.
The University of California is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, age or protected veteran status. For the complete University of California nondiscrimination and affirmative action policy see: http://policy.ucop.edu/doc/4000376/NondiscrimAffirmAct
The Department is interested in candidates who will contribute to diversity and equal opportunity in higher education through their research or teaching.
The University of California, Berkeley has an excellent benefits package as well as a number of policies and programs in place to support employees as they balance work and family.
[posted Apr 25, 2017]
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